QuickMice™ fast KI mouse customization

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Quickmice™ Fast KI Mouse Customization

Knock-in (Knock-in, KI) is a technique that utilizes homologous recombination of genes to transfer an exogenous functional gene into a homologous sequence in the cell and genome, and obtain expression well in the cell after gene recombination.

It takes 5-6 months to obtain Neo-deleted heterozygous mice and a total of 10-12 months to construct a KI homozygous mouse models with low success rates using traditional techniques, because these techniques have low chimera positivity and require mating with a mouse to obtain Neo-deleted heterozygous mice, and then breeding the born heterozygous mice for 2-3 generations to get the homozygous KI mice.

A New generation of Rapid Mouse Preparation Technology

TurboMice™

We can quickly provide you with KI homozygous mouse models by applying TurboMice™ technology to improve the success rate.

Based on the optimal gene editing program by our scientists, we can complete the screening of edited embryonic stem cells within 3-5 days, then construct tetraploid embryo. After maternal surrogacy, the homozygous humanized mice can be obtained within 2-4 months, which can save 7-8 months for customers.

Service Content

Service No.	Technical indexes	Delivery content	Delivery cycle
MC002-1	length of single gene <5kb	3-9 KI homozygous male mice	2-4 months
MC002-2	length of single gene <5kb	10-19 KI homozygous male mice	2-4 months
MC002-3	length of single gene <5kb	20 KI homozygous male mice	3-5 months
MC002-4	length of single gene is 5kb-10kb	3-9 KI homozygous male mice	3-4 months
MC002-5	length of single gene is 5kb-10kb	10-19 KI homozygous male mice	3-4 months
MC002-6	length of single gene is 5kb-10kb	20 KI homozygous male mice	3-5 months

Contact Us

Please get in touch with us at:

1) Please download and fill out the form below《Quotation Request Form》, and send it by email to MingCelerOversea@mingceler.com;

2) Te: +86 181 3873 9432;

3) LinkedIn: https://www.linkedin.com/company/mingceler/

Quotation Request Form. docx

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